Stability Chambers – PH Series

The Darwin Chambers PH Series Stability Chambers are designed for performance specifications exceeding FDA and ICH requirements. For GMP studies, ultrasonic humidification provides excellent humidity control and avoids hot spots during mapping. Thermoelectric cooling provides more stable temperature control than equivalent refrigeration systems. All PH series chambers incorporate inherent cooling redundancy, quiet operation, simple serviceability and excellent reliability.

The PH Series from Darwin Chambers was introduced nearly 20 years ago as the first large capacity thermoelectric cooled pharmaceutical stability testing chamber. Thousands of our stability chambers are presently in use by many pharmaceutical, cosmetic, nutraceutical, medical device, therapeutic pharmaceuticals, pharmaceutical stress testing, and other research companies around the world. The advantages of these chambers for stability or shelf life testing are substantial.

We build chambers to meet very specific requirements in a wide variety of industries. The PH Series chambers are our most popular offering for good reasons. These chambers produce exacting results and we provide support for them with timely quoting, quick lead times, reliable insulation, trusted validation services, and superior product support in the future. Please do not hesitate to inquire for any further information that may not be provided on our website.



The PH03 is an undercounter stability chamber.



The PH011 is a bench top stability chamber designed to fit on 24” benchtops or stacked with optional racking.



The PH030 is a single-door stability chamber.



The PH034 is an extra wide single-door stability chamber.



The PH055 is a 2-door stability chamber.



The PH068 is a 2-door stability chamber.



The PH084 is a 3-door stability chamber.

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Frequently Asked Questions (FAQs) About Stability Chambers

What Are the Types of Stability Chambers?

Stability chambers are built to regulate precise temperature ranges from -20°C to 94°C (-4°F to 201°F) and humidity control. At Darwin Chambers, we prioritize these specifications when constructing and installing custom stability chambers tailored to your installation and stability testing requirements.

Our range of stability chambers includes:

  • Walk-In Chambers
  • Temperature-Humidity Chambers
  • Environmental Chambers
  • Photostability Chambers
  • Thermal Shock Test Chambers
  • Anechoic Stability Chambers
  • Vacuum Chambers
  • Vibration Chambers

Learn more about our stability chambers and stability refrigerators, and how we create a controlled and consistent environments for product testing and research experiments.

What Are Stability Chambers Used For?

Pharmaceutical companies would use these chambers to pass FDA/ICH regulations. Having complete control over temperature, humidity, and light exposure is key for companies researching and developing new drugs. We're able to replicate real-world situations where your drugs operate under direct testing. For pharmaceutical companies, this might include:

  • Packaging Integrity
  • Compliance Testing
  • Quality Testing
  • Product Development Systems
  • Heat and Light Exposure
  • Product Lifespan and Shelf Life Testing

Other industries might use stability chambers for:

  • Quality Assurance Testing
  • Purity / Potency Testing
  • Product Development
  • Aging Studies (Expiration Dates)
  • Compliance Testing
  • Packaging
  • Potency

How Does Stability Testing Work?

Accelerated stability and ICH testing entails subjecting a product to heightened stress conditions, such as elevated temperatures and/or humidity levels. By doing so, degradation patterns under recommended storage conditions can be anticipated by utilizing established correlations between the acceleration factor and degradation rates.

The key word here is accelerated. Products that are stored in stability chambers "age" and are affected by various controlled conditions. This testing is incredibly important in the pharmaceutical industry. Your drugs could degrade or be compromised by environmental hazards like air pressure, humidity, and sunlight. It's important to meet particular guidelines in order to safely produce and sell drugs at retail. Drug manufacturers are often required to show shelf life results that come from stability tests in order to pass FDA/ICH regulations.

The standard order of operations of stability chamber tests includes:

  • Sample Selection
  • Stress Conditions
  • Monitoring and Analysis
  • Data Collection
  • Establishing Shelf Life
  • Meeting Regulatory Compliance

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